With the Nexus Pearl, I had to completely rethink my lines. Basically, I had to stand farther left, and throw farther right overall, but at a spot farther down the lane than anything else I've ever thrown. Now, I have decent hand and only medium speed, but usually that equates to checking up early, not coast-to-coast power.
It's not a ball I would go to if my goal is to throw a tight 10 board-wide line center-right of the head pin. That's Versa Max territory right there. While they are two very different balls, I can see how the Versa Max would be useful for more bowlers in more situations than the Nexus...but again, its versatility is in throwing lines on conditions you've never thrown before (at least for me).
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Arsenal: Nexxus P+R, Nexus Pearl, Versa Max, BVP Punisher, Power Groove Dry/R, XXXL Starburst