The 4E and 4L drillings are mainstays in my arsenal. For me, these are the prototypical "control" drillings. Both layouts give me a clean look in front. The 4L tends to be a bit longer, and a bit stronger at the break, so I'll use the 4L on broken-down conditions where I still need some pop down the lane, and the 4E when the fronts are choppy but there's some wet-dry in the midlane or in back.
I don't usually go with the 3L layout by design, as it's essentially a 4L with a flare-increasing XH. If I'm looking for more flare, I'll just use the 2L instead. However, I have on occasion turned the 4L into the 3L by adding the hole.
Hope this helps.
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...formerly "The Curse of Dusty," and "Poöter Boöf" before that...