I would worry that if a short pin layout takes out too much flare, than can get carry down with reactive.
When I switched to no-thumb, I bought a Columbia Scout as weak reactive to help me learn. It didn't flair and produced tremendous carry down.
This would have never happened when using my thumb, but a ball with 400 RMPs and low tilt (as common with no-thumb bowlers) has so much surface to grab oil in the front, and it it doesn't flare can dump a lot on back end.
I practice a lot with a cyclone with has a low flare layout. If the lanes are dry, it breaks down like usual. But if I ever get change to practice with it on fresh, after a game or two I need to move right just like urethane.
Later used cherry vibe with 2 inch pin to PAP, very controllable. It's not exactly like urethane, but a stronger version of Covert Tank (which is not urethane either). But that ball still flares.
Anyway, I suspect if the goal is to avoid carrydown, it may be better to use a "urethane like" ball the flares (covert tank, badger infused) than a reactive ball with a low diff and short pin-PAP. But I haven't drilled all these options to compare so don't know.
I do know for sure that high rev, low tilt bowlers using a low flare reactive can cause quit a lot of carry down.
Back when I used my thumb and had a 220 rev rate, I didn't even think carry down was much of a real thing. Even using urethane I never produced it.