As long as you're referring to a new ball where you can do the layout as directed you should be fine.

The major caution is the studies haven't been completed with asymmetric equipment.  People have had less than spectacular results in equipment where the core in the ball isn't completely symmetrical.

As I've said before, this isn't the best forum for this sort of question.

Took an old Innovate and went MOtion hole on it last night. Huge difference with the angle, continuation and overall hitting power. Even my son said that it sounds different when it goes through the pins. For someone who is speed dominant like me, who know his game and who pays attention to the successful/non successful parts of the lane to play, this change might be the 5-10 pins I am looking to gain.