Bill,
1. Yes, the tracking is hilarious. Since it was new to me, I was flipping the ball all around and using all six configurations. As such, the ball had lines going every which way. Clearly, I will have to wipe the ball down after every shot (maybe even using one of the "approved during use" cleaners) and give it a good cleaning after each set: otherwise, that ball can/will have gunk on just about every inch of the surface.
2. We kept the layout pretty basic for this first one. We basically went 12-6, 1:30-7:30, 3-9, and 4:30-10:30. We considered starting with a slight shift off of that in order to bring in different characteristics, but, again, since it was the first ball we've played with like this, we thought it best to stay simple. If we do others, we'll likely play around a bit more.
I definitely saw reaction differences, but it's going to take some time and practice to really hash it out, especially since no-thumb is something that I've just started experimenting with again. For now, it would be more beneficial to watch someone who has a finely-honed no-thumb delivery since he or she can repeat shots better than I can at this point.
On a side note, my driller also pointed out that a doubles team, whether it be two righties, two lefties, or one of each, could use the same ball(s) and simply flip the layouts around as long as their fingers were of comparable size. That would be too funny to watch!