Several years ago, I tried a conventional grip on a pearl reactive ball. The release is totally different. If you like to turn the ball, you'll have a hard time with consistency. To get consistency you have to stay behind the ball and just roll it. Since you don't get much leverage, the ball won't get into a decent roll till it's past midlane (depends on how dry the heads are). Once the ball starts rolling it did get a decent backend reaction (dependent on ball layout).
I did have minor success with it. It's pretty funky and people do give you strange looks. Should of since the faces of my biggest critics when I shot 299 and a 752 series.
Buy a cheap used ball and try it,practice with it for a month and see if it can work for you. If not you can go back to old reliable, or it becomes another weapon in your arsenal.