I am curious of different drillings and the comparison of drillings for a 2 hander compared to 1 hander. Does the layout matter with the reaction from the release of a 2 hander compared to 1. Even a regular no thumber?

thanks
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High game 300, 298(no middle finger) 290, 290(no middle finger)
High series 804
High triplicate 774
High average 221
best game. when I was 6 I bowled a 158

I have a 16# morich awesome finish I want to trade.  1 season on it.    I am looking for 15# stuff