One guy did that in our summer league a couple of years ago. Was a 220 avg righty who did lefty for the summer and averaged 160, don't know if there was any difference in the weight he used. Rather than switching hands, I am just wondering, if it would be possible, and perhaps easier somehow, to alter your footwork so you would end up on the opposite foot, I imagine that would feel really weird to do so, but might give better bowling results than switching hands.
Brad