I have seen pre-drilled house balls, but not slugs. Assuming they are available, that would be fine if your thumb was just a round hole with a slight finish sand. Most people have some type of bevel or other finishing work that they do to the thumb hole that can account for slight differences.
It is the finish work, combined with normal human "error", as well as amount of sanding or bevel, speed of the drill, how fast the operator drills the hole, and how sharp the bit is, how worn the jig and press are, can all account for small variations in thumb feel, dimension and pitch.
In my opinion, a decent operator with decent equipment, should be able to get all span and pitch measurements within 1/16 of an inch, from ball to ball.