I've tried a number of layouts over the last 3 years; 1 x 1, 4 x 4, pin over bridge w/ cg in and out, pin under bridge, pin negative, cg negative, etc. About the only on I really didn't like (and it was probably just wrong for the ball) was pin negative, cg positive on a Roto SSPearl. Everything else was just fine, on the right condition.
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