for the normal house shot and sometimes ez tourney shot it is by far easier to just hook at the left/right sleepers. on the THS ur ball will recover from bad shots and will still give you a shot at picking up the spare. however, if you come across a sport shot or tougher pattern it is by far easier to just throw plastic straight at it or at a slight angle, but you still have to be very accurate.
pros normally throw straight at sleepers cuz it basically takes out the guess work of the pattern. pros bowl on much tougher patterns so it is prlly more consistent if they just throw straight, and not worry about how the condition will affect their ball if they hook at the sleeper or any other spare. you have to remember though that these guys are pros for a reason, they are way more accurate than you or me.
i think for the average bowler it will prlly be easier to just hook at the sleepers, you will prlly get more than you miss in the long run. personally, i can do both, but am much more comfortable just hooking at the sleepers. but if the pattern is tuff or im missing the sleeper consistently, i will just throw my spare ball straight to cover the sleeper.