Generally speaking, house shots don't require anywhere near the level of precision that is required on PBA patterns. As such, any "normal" drilling layout can get the job done. There really isn't any such thing as a specific layout for PBA patterns. The pros use layouts that they've found work well for their specific styles. Then they match them up with the proper bowling ball surface and ball type in order to give them the reaction they're looking for on whatever oil pattern and lane surface they're competing on. The way your question is worded makes it sound as if there are certain drilling layouts or balls for the PBA patterns, and that's not the case. It's always about matching ball surface, drilling, ball type, and bowler style to the oil pattern and surface being bowled on. As such, a ball drilled for a specific PBA pattern isn't likely to create an advantage on your house shot because even if the characteristics of your house pattern are similar to that of one of the PBA patterns, you still have to factor in your individual characteristics as a bowler. Not all drillings work for all bowlers.
Lastly, pros do make adjustments as opposed to just grabbing different bowling balls, but both moves are required. Today's bowling balls are much more specialized then those of the past. As such, they're treated more like golf clubs. You have certain balls for certain situations. Imagine telling a golfer he or she should just use a 7-iron for all shots in a round. Sure, you could get around the course, but you're not using the ideal tool for the various shots you need to throw. Expecting pro bowlers to use 1 ball for all circumstances is equally unrealistic.