The vast majority of bowlers never play a breakpoint outside of the five board, so they would play the lanes as they always do. Of the rest, many of them only get to a breakpoint at or outside of the five board when they make a mistake. As such, their intended line to the pocket would be the same, they simply wouldn't be able to make the mistake outside of five and get away with it.
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J.J. "Waterola Kid" Anderson, the bLowling King : Kill the back row