I have drill spans of 5 1/2 (middle finger), 5 5/8 (ring finger) and thumb pitches of 1/8 lateral, 5/8 reverse; zero pitch in the fingers, but 1/2 and 3/8 lateral in the fingers, respectively. (I've had as much as 3/4 reverse in the thumb, but I've settled on 5/8 reverse.)
Former touring pro Don Genalo has a similar span but he has zero reverse thumb, 1/2 lateral pitch. He's said he's able to go with zero pitch because he's double jointed in the thumb. Go figure.
I've had people to tell me that I have too much reverse pitch in the thumb, and I tell them they have no clue what they're talking about. First of all, my span is usually an inch or more longer than theirs.