The house I learned to bowl in, an ancient 10-lane house, had a reputation -- Lane 6 was known as the "hook lane" or the "ghost lane."
You could take any bowling ball, drilled any way you please, and roll it slowly down the right side. It would curve left about 5-8 boards every time from the front of the lane to the back. The lane was either warped or tilted.
For some reason, it always passed inspection every year, but it always had that hook characteristic to it.
Did it help or hurt when actually bowling on it? Hard to say. I never got good enough before I left there to either make use of it or be put in a position to have to fight against it. I sprayed the ball around like an idiot back then. We never saw scores from that pair significantly higher or lower than the rest of the house, either.
But I could definitely see it being possible.
Jess