Nothing changes, as far as span goes or the layout of the ball, when drilling a CLT grip. Map out your ball with span lines as you normally would do before drilling.
The only thing different is instead of drilling the fingers using the line from the center of the bridge to the center of your thumb, a new center line is used. This line will go from the center of your bridge, to the right of your thumbhole.
Drill the thumbhole. Place your thumb in the thumbhole and lay your fingers over the ball with the fingers pointing towards where the finger holes will be drilled. Now, draw a line right down the center between your middle and ring finger. This will be your new center line.
When drilling the fingers, turn this new center line so it will be facing 12:00 and 6:00 in your jig. Now drill your fingers using the same span lines as was marked originally on the ball going towards the center of your thumbhole. This is how you drill a CLT grip.
Basically, all you're doing is changing the pitches of the holes, without changing the pitches on your jig. Just ask Brian Omara..!! =:^D