charlest, I don't have the Scream, but I have both Ascents (solid and pearl) drilled exactly the same.
The pearl is a predictable step down from the solid. When I have a good look with the solid and the mids start to go, I can switch to the pearl and continue with the same look. It's a nice 1-2 punch when the Ascent is the right match to the lanes.
What I find interesting is the there isn't always a predictable connection between the solid/pearl versions of the same ball. I also have the Motiv Primal Impulse (pearl) and the Primal Scream (solid) drilled the same. The Primal Scream rolls much heavier and has a different feel, even on much more oil. I like it, but it doesn't fit the 1-2 punch like I get with the Ascents. Go figure....