You most assuredly can put the MB anywhere and alter the reaction. That's why we have strong asymmetric balls.
But it still has to be legal. And some of those reactions may not be very desirable. Putting the MB on a strong asym in your track or PAP can do goofy things to the way the ball flares.
Really, you're limited to putting it on some half of the ball. When it moves to some other half of the ball, the spot 180* from the MB is back on the first half. Remember the MB is also called the Preferred Spin Axis, that axis goes all the way through the ball and there is a second mass bias on the other side.
SH