If it's just your fingers, yes Vacu-grips could help. if it's your thumb, try something like Ron Clifton's Magic carpet thumb tape that will compress a little if your thumb swells to still allow a quick release.
--------------------

I switched to Vacu-grips a few weeks ago.  I was able to get used to them after about five frames, and I shot my first 800 series just one week later.  Love, love, love the Vacu-grips.

I used to have trouble with my hand swelling a lot, but I reduced that with a little shorter span, a little less reverse in the thumb to lock my hand in more securely, 1/8" reverse in my fingers, and Vise Hada patch on the back of my thumb to reduce friction and drag on my thumb.  It's nowhere near as bad as it used to be, I was able to bowl 21 games in a tournament awhile back with zero swelling problems.

I am 4" middle, 4 1/8" ring, no pitch, 45 degree oval.  Shorter seems to put MORE stress on my hand.  I'm already in a relaxed finger tip.  Also, when I bowl a tourny, my breakfast is always the same, a wheat bagle and an ice mocha latte from dunkin' donuts.  lol