I am bowling as a sub in a league tomorrow night. Its at a house I have never bowled at before.

Whats the quickest way to find out what the lanes are doing and get setup quickly?

I mean they only give you 10 minutes of practice, I don't want to be half way through the first game and still trying to figure out the lanes.

What should I do?

I wish I had 10 min of practice...the house I do most of my bowling at only gives 5 min, and have the slowest pin setters on earth...plus the shot is different each week...my goal by the end of practice, which is normally 4 balls, is to have the ball feel good coming off my hand...

to your question, i would just start at your usual starting point at your home house, and work from there...if you can't find the pocket by adjusting off your normal strike line you'll have to try moving further inside, or outside...you may be best off asking someone what the normal conditions are for that league...