My 2 cents: Err on the side of strength with this ball.
I'm a solid tweener, medium speed, decent revs, PAP about 5" over.
I drilled my Pluto for a very specific condition. In one house I bowl in, the (wood) lanes are absolutely flooded inside of 9 or 10, so everyone is throwing dull solid balls between the first and second arrows. By about the middle of the second game, we get a combination of burned heads and carry-down. Moving in just doesn't work, even with a Cell or Dimension, and you can't swing around the heads because if you miss right the ball will jump and if you miss left the ball will skid into the 3 pin.
I came up with the idea of a Pluto drilled real long/weak. Pin is over my middle finger (about 6" from PAP) and CG is just above grip center no weight hole. Once the heads burn, I can switch to the Pluto and still play fairly straight up the track. The solid cover doesn't grab as hard as a pearl would on the dry heads, and then the ball just rolls and arcs downlane. Carry is amazingly good.
Whenever I've tried to throw this ball on any fresh or reasonably normal pattern, it goes very, very long, sometimes never turning at all. Very unpredictable. If I wanted to use a Pluto for a normal condition, I would drill it strong, probably 4x4. With the combination of cover and core, I can't see it over-reacting, plus the cover could be tweaked, polished, etc.
-Scott in Pennsylvania