The CG typically doesn't do much for you on balls with a strong MB.  I would say the placement of the MB will have more influence on reaction than CG.  Just make sure your statics are good.

rackattack:

This is not Roto's opinion but my own after years of drilling and experimenting on  hundreds of balls.  Ignore the CG.  If it's a asymmetrical ball, make sure the MB is placed to match the breakpoint shape you want. If it's symmetrical, place the CG (say with 3/4oz ending side) in such a way so that if you need a weighthole,  you can later tweak the reaction.  

Just to give you a heads up in case because it's not clear what you mean by "above my Angular One".  You'll get a different look from the Horizon than the Angular One because of coverstock and core differences.  I had an Angular One before joining Roto.  The AO is a strong asymmetrical pearl which means it's really strong downlane.  The HS is a sanded solid that's strong throughout the whole lane.  It's more midlane read.  The AO may end up hooking more because of how many boards it covers in the backend.  If you wanted more overall hook but with the same strong backend, then the Odyssey is the perfect choice.
--------------------
Anthony Chapman

Roto Staff 2007
Videos coming soon...As soon as my son can hold the camera

I have a RSX drilled up with the CG just right of grip center Pin right of ring.  According to the drill sheet this would place the MB under the thumb, maybe a tad to the left.  I got it used so I didn't want to lay out the cash to have the entire thing plugged so i=I just moved the thumb.  I was concerned at first that putting the MB there would really tame the ball.  But in reality the ball moves like no other.  Nice midlane and giant backend.

I'm no expert but why would a MB really matter on a symmetrical ball?