Yes.
Mainly due to the fact that the Fusion has a much lower RG and a lower RG Differential, for most of the ball weights. Once you get down to 14 lb. balls, the difference in RG differential is less significant, but the difference in RG is greater.
If you drilled the Fusion normal (3.5 - 4.5" pin-PAP and medium VAL angle) and if you drilled the LO with a longer pin-PAP (5 - 5.5") and shorter/smaller VAL Angle, when the lanes get too dry for the Fusion and its drilling won't let you play deeper, the LO should enable you to move deeper and make a strong turn in the back.
Thinking of buying another Lights Out?