I drilled my Paradox Trilogy with the pin above the middle finger and slightly to the right. Not quite above the bridge but kind of in between, and the CG on the right side of the palm, Mass Bias about half an inch to right of thumb hole.
When first testing the ball, I was on a fairly fresh house pattern. It had been used as breakdown pair the night before but not been used for league. It may have had one or 2 people put on it for open play. So it was fairly fresh. I threw my first few shots where I normally would start with other stuff and it hooked way too much. Eventually as i got warmed up I noticed that the ball carried off hits very well and pins would scatter across the deck.
I drilled a fresh 503T about 2 months ago with the exact same layout and the Trilogy is a good 4-6 boards stronger overall. It gets down the lane better and has more of a backend.